Sleep down state-active ID2/Nkx2.1 interneurons in the neocortex

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Title: Sleep down state-active ID2/Nkx2.1 interneurons in the neocortex

Authors: Manuel Valero, Tim J Viney, Robert Machold, Sara Mederos, Ipshita Zutshi, Benjamin Schuman, Yuta Senzai, Bernardo Rudy, György Buzsáki

Journal: Nature Neuroscience

Abstract: Pyramidal cells and GABAergic interneurons fire together in balanced cortical networks. In contrast to this general rule, we describe a distinct neuron type in mice and rats whose spiking activity is anti-correlated with all principal cells and interneurons in all brain states but, most prevalently, during the down state of non-REM (NREM) sleep.

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Publication URL: https://www.nature.com/articles/s41593-021-00797-6

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Publication date: 2021-02-22

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