Help & Documentation

NREM sleep in the rodent neocortex and hippocampus reflects excitable dynamics

Home › Dissemination › Publications › NREM sleep in the rodent neocortex and hippocampus reflects excitable dynamics
NREM sleep in the rodent neocortex and hippocampus reflects excitable dynamics
D Levenstein, G Buzsáki, J Rinzel
During non-rapid eye movement (NREM) sleep, neuronal populations in the mammalian forebrain alternate between periods of spiking and inactivity. Termed the slow oscillation in the neocortex and sharp wave-ripples in the hippocampus, these alternations are often considered separately but are both crucial for NREM functions. By directly comparing experimental observations of naturally-sleeping rats with a mean field model of an adapting, recurrent neuronal population, we find that the neocortical alternations reflect a dynamical regime in which a stable active state is interrupted by transient inactive states (slow waves) while the hippocampal alternations reflect a stable inactive state interrupted by transient active states (sharp waves).
2019-06-06
back
Help

BrainSTEM (Brain STructured Experimental Metadata) is a collaborative electronic lab notebook for FAIR experimental neuroscience. It has a customizable web interface and a standardized yet flexible data model and is designed to capture a range of electrophysiology, imaging, and behavioral data. Granular permissions, including one-click public sharing, promote collaborations and open science. BrainSTEM is designed with ease of adoption and use as a primary consideration and facilitates compliance with NIH and other data-sharing requirements.

BrainSTEM can accelerate your science, promote collaboration, extend the lifetime of your data, and make FAIR data sharing easy. Please see the dedicated documentation website at below link.